Maxim - the main hero of Lufia II. Maxim is a monster hunter from the little town of Elcid. As long as he can remember, he has been an expert swordsman, even though he has never received any training. His biggest worries are keeping monsters away from the village and keeping his childhood friend Tia happy. But one day, mysterious lights are seen in the sky - no, not aliens, but something more sinister. Then, the monsters in the North Cave leading to the next village start getting aggressive. Maxim goes to quell them, but he meets a mysterious woman who tells him he is destined to fight, to save humanity. Maxim must journey across Lufia to meet people who can help him turn back the tide of history that threatens the very existence of humans.

Tia - Tia is Maxim's friend and the owner of the weapons store in Elcid. She also is in love with Maxim, a state that will undoubtedly try her patience for a long time to come. Tia can't stand watching Maxim go off into battle, knowing that he might not come back. While not a very strong fighter, Tia does have the ability to use more magic than Maxim does; for instance, the spell Spark, which Maxim can't use, is one of the first spells Tia can purchase.

Iris - A mysterious woman with magic powers. Maxim meets Iris in the cave to Sundletan; she tells him that he is destined to fight against an evil that threatens all of humanity. Iris appears often around Maxim, nudging him in the right direction and sometimes helping him when the situation is dire. The extent of her powers and her true identity is unknown, but she is generally a benevolent influence.